Tuesday 12 August 2008

Antibiotics During First Three Months Of Life Linked To Wheezing At 15 Months - Likely Due To Underlying Infection

�Children wHO are minded antibiotics in their first base three months often wheeze at 15 months of age. However, this wheezy is in all probability more due to the presence of chest infections than to the economic consumption of antibiotics.


These were the winder findings of research carried out by researchers in New Zealand, and published in this month's variant of Clinical and Experimental Allergy. This work reinforced on the fact that the prevalence both of asthma and the use of antibiotics have risen since the 1960s. Using antibiotics reduces a person's exposure to bacterial infections and disturbs healthy populations of bacteria in the body, and the question is whether this and so leaves a person more prone to develop asthma attack.


The researchers recruited a group of 1,000 babies at birth and contacted the parents at 3 months, 15 months and then yearly until they were four years old. Each time, they collected information about chest infections, asthma and their use of antibiotics. The data showed that by the clip the children had reached 15 months old, near three quarters (72.1%) had been given antibiotics. In addition 11.8% had asthma attack, 39.6% had eczema and 21.2% had a revenant itchy scabrous rash.


The researchers then looked at the information to see whether there was whatever indication that the antibiotics caused these effects and found that by adjusting for the effects of chest infections the association between antibiotics and wheezy was selfsame much reduced.


"Our results strongly intimate that the reason that some children who have got been given antibiotics appear to grow asthma is because they had a chest transmission and the symptoms of the dresser infection in young children can be confused with the start of asthma attack," says Julian Crane, a senior study investigator at the Wellington Asthma Research Group in Wellington, New Zealand. "Antibiotics are disposed to treat the respiratory condition and rather than being a cause of asthma, as has been previously suggested, they are used for chest infections which commode indicate an increased danger of bronchial asthma, or be mistaken for it."


One of the underlying issues is that it is often difficult to differentiate between bronchial asthma and breast infections at an other age. Consequently some infants who are given antibiotics to cure a chest infection may really have been suffering from the early symptoms of asthma attack.


"Our information still leaves open the possibility that antibiotics may affect the development of eczema and itchy skin by four-spot years and allergic hypersensitivity by 15 months," says Crane.

Wiley-Blackwell


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